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The following term was not found in PubMed: MEA5
Page 1
TGFBR3 and MGEA5 rearrangements in pleomorphic hyalinizing angiectatic tumors and the spectrum of related neoplasms.
Carter JM, Sukov WR, Montgomery E, Goldblum JR, Billings SD, Fritchie KJ, Folpe AL. Carter JM, et al. Am J Surg Pathol. 2014 Sep;38(9):1182-992. doi: 10.1097/PAS.0000000000000212. Am J Surg Pathol. 2014. PMID: 24705316
HFLT, myxoinflammatory fibroblastic sarcoma (MIFS), and tumors showing hybrid features of HFLT and MIFS often show TGFBR3 and MGEA5 gene rearrangements. To date, only a small number of PHATs has been tested for either rearrangement; all have been negative. ...Six of …
HFLT, myxoinflammatory fibroblastic sarcoma (MIFS), and tumors showing hybrid features of HFLT and MIFS often show TGFBR3 and MGEA5 …
Network-based method for drug target discovery at the isoform level.
Ma J, Wang J, Ghoraie LS, Men X, Liu L, Dai P. Ma J, et al. Sci Rep. 2019 Sep 25;9(1):13868. doi: 10.1038/s41598-019-50224-x. Sci Rep. 2019. PMID: 31554914 Free PMC article.
However, the literature reports limited effort to identify the target major isoform of a single known target gene. The majority of genes generate multiple transcripts that are translated into proteins that may carry out distinct and even opposing biological function …
However, the literature reports limited effort to identify the target major isoform of a single known target gene. The majority of …
Gene and protein expression of O-GlcNAc-cycling enzymes in human laryngeal cancer.
Starska K, Forma E, Brzezińska-Błaszczyk E, Lewy-Trenda I, Bryś M, Jóźwiak P, Krześlak A. Starska K, et al. Clin Exp Med. 2015 Nov;15(4):455-68. doi: 10.1007/s10238-014-0318-1. Epub 2014 Oct 15. Clin Exp Med. 2015. PMID: 25315705 Free PMC article.
The aim of this study was to determine the expression of O-GlcNAc cycling enzymes mRNA/protein and to investigate their relationship with clinicopathological parameters in laryngeal cancer. The mRNA levels of OGT and MGEA5 genes were determined in 106 squamous cell …
The aim of this study was to determine the expression of O-GlcNAc cycling enzymes mRNA/protein and to investigate their relationship with cl …
The hexosamine biosynthesis pathway-related gene signature correlates with immune infiltration and predicts prognosis of patients with osteosarcoma.
Su Z, Wang C, Pan R, Li H, Chen J, Tan J, Tian X, Lin T, Shen J. Su Z, et al. Front Immunol. 2022 Oct 6;13:1028263. doi: 10.3389/fimmu.2022.1028263. eCollection 2022. Front Immunol. 2022. PMID: 36275679 Free PMC article.
RESULTS: Through GSVA and survival analysis, the HBP pathway was identified as the significant prognostic related metabolism feature. Five genes in the HBP pathway including GPI, PGM3, UAP1, OGT and MGEA5 were used to construct the HBP-related risk model. ...When sc …
RESULTS: Through GSVA and survival analysis, the HBP pathway was identified as the significant prognostic related metabolism feature. Five …
Gene expression of O-GlcNAc cycling enzymes in human breast cancers.
Krześlak A, Forma E, Bernaciak M, Romanowicz H, Bryś M. Krześlak A, et al. Clin Exp Med. 2012 Mar;12(1):61-5. doi: 10.1007/s10238-011-0138-5. Epub 2011 May 13. Clin Exp Med. 2012. PMID: 21567137 Free PMC article.
Cycling of O-GlcNAc residues on intracellular proteins is controlled by two enzymes, O-GlcNAc transferease (OGT), which catalyses the addition of O-GlcNAc residues and nucleocytoplasmic beta-N-acetylglucosaminidase (O-GlcNAcase; encoded by MGEA5 gene), an enzyme inv …
Cycling of O-GlcNAc residues on intracellular proteins is controlled by two enzymes, O-GlcNAc transferease (OGT), which catalyses the additi …
TGFBR3 and MGEA5 rearrangements are much more common in "hybrid" hemosiderotic fibrolipomatous tumor-myxoinflammatory fibroblastic sarcomas than in classical myxoinflammatory fibroblastic sarcomas: a morphological and fluorescence in situ hybridization study.
Zreik RT, Carter JM, Sukov WR, Ahrens WA, Fritchie KJ, Montgomery EA, Weiss SW, Folpe AL. Zreik RT, et al. Hum Pathol. 2016 Jul;53:14-24. doi: 10.1016/j.humpath.2016.02.005. Epub 2016 Mar 2. Hum Pathol. 2016. PMID: 26980036
Using previously validated break-apart fluorescence in situ hybridization probes, we analyzed for TGFBR3 and MGEA5 rearrangements. Only 2 of 31 MIFSs harbored MGEA5 rearrangements; all lacked TGFBR3 rearrangements. Six of 8 hybrid HFLT-MIFSs harbored rearrangements …
Using previously validated break-apart fluorescence in situ hybridization probes, we analyzed for TGFBR3 and MGEA5 rearrangements. On …
Consistent t(1;10) with rearrangements of TGFBR3 and MGEA5 in both myxoinflammatory fibroblastic sarcoma and hemosiderotic fibrolipomatous tumor.
Antonescu CR, Zhang L, Nielsen GP, Rosenberg AE, Dal Cin P, Fletcher CD. Antonescu CR, et al. Genes Chromosomes Cancer. 2011 Oct;50(10):757-64. doi: 10.1002/gcc.20897. Epub 2011 Jun 29. Genes Chromosomes Cancer. 2011. PMID: 21717526 Free PMC article.
Fluorescence in situ hybridization (FISH) analysis for rearrangements of TGFBR3 on 1p22 and of MGEA5 on 10q24 was performed in all cases, whereas the status of VGLL3 gene amplification on 3p12.1 was investigated in 12 cases. ...Overall 83% of cases showed rearrangem …
Fluorescence in situ hybridization (FISH) analysis for rearrangements of TGFBR3 on 1p22 and of MGEA5 on 10q24 was performed in all ca …
Myxoinflammatory fibroblastic sarcoma: morphologic and genetic updates.
Ieremia E, Thway K. Ieremia E, et al. Arch Pathol Lab Med. 2014 Oct;138(10):1406-11. doi: 10.5858/arpa.2013-0549-RS. Arch Pathol Lab Med. 2014. PMID: 25268202 Free article. Review.
Distinct and reproducible genetic abnormalities identified in MIFS are translocation t(1;10)(p22:q24), with rearrangements of the TGFBR3 and MGEA5 genes associated with increased levels of FGF8, and formation of marker/ring chromosome 3, with amplification of the VG …
Distinct and reproducible genetic abnormalities identified in MIFS are translocation t(1;10)(p22:q24), with rearrangements of the TGFBR3 and …
The t(1;10)(p22;q24) TGFBR3/MGEA5 Translocation in Pleomorphic Hyalinizing Angiectatic Tumor, Myxoinflammatory Fibroblastic Sarcoma, and Hemosiderotic Fibrolipomatous Tumor.
Liu H, Sukov WR, Ro JY. Liu H, et al. Arch Pathol Lab Med. 2019 Feb;143(2):212-221. doi: 10.5858/arpa.2017-0412-RA. Epub 2018 Jul 6. Arch Pathol Lab Med. 2019. PMID: 29979612 Free article.
Translocation t(1;10)(p22;q24) involves transforming growth factor beta-receptor 3 ( TGFBR3) and meningioma-expressed antigen 5 ( MGEA5) genes on chromosomes 1p22 and 10q24, respectively. However, the percentage of translocation in PHAT, HFLT, and MIFS varies signif …
Translocation t(1;10)(p22;q24) involves transforming growth factor beta-receptor 3 ( TGFBR3) and meningioma-expressed antigen 5 ( MGEA5 …
Novel immunogenic antigen homologous to hyaluronidase in meningioma.
Heckel D, Comtesse N, Brass N, Blin N, Zang KD, Meese E. Heckel D, et al. Hum Mol Genet. 1998 Nov;7(12):1859-72. doi: 10.1093/hmg/7.12.1859. Hum Mol Genet. 1998. PMID: 9811929
In humans hyaluronidase has been implicated in cancer development and three human genes are known to encode proteins with hyaluronidase activity. None of the human genes, however, showed any homology at the nucleotide or amino acid sequence level to the newly isolat …
In humans hyaluronidase has been implicated in cancer development and three human genes are known to encode proteins with hyaluronida …
19 results